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According to Eve and Mordin, the krogan would have been a whole lot more peaceful had they been allowed to advance scientifically at their own pace, instead of being "uplifted" by the salarians to fight in a nasty war.
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Unfortunately, the violent nature of krogan life tends to keep them from taking advantage of this: if a krogan has lived to an old age, you know messing with them is a bad idea. Wrex and Okeer are veterans of the Krogan Rebellions, making them both over 1467 years old, and Wrex's father is implied to have lived even longer than that.
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